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Is the New Balance U500 vegan?

Not from what we can see. All 4 New Balance U500 colourways we checked contain an animal material such as leather or suede.

Contains animal materials (4)

Listed so you can rule them out. The reason is shown on each.

U500 black faded black/blacknot vegan
black faded black/black
Leather and textile · lining Textile · sole Synthetics
materials list: Leather
GM500ZB2 · resale from $116
U500 stoneware thunder brown/light brownnot vegan
stoneware thunder brown/light brown
Leather and textile · lining Textile · sole Synthetics
materials list: Leather
U500 white/slate grey/whitenot vegan
white/slate grey/white
Leather/synthetics · lining Textile · sole Synthetics
materials list: Leather
U500 white/vintage indigo/whitenot vegan
white/vintage indigo/white
Leather/synthetics · lining Textile · sole Synthetics
materials list: Leather
Checked against retailer listing data. Glues and dyes are not declared by any brand and cannot be verified. How we check.